{"id":2266,"date":"2020-10-05T16:37:29","date_gmt":"2020-10-05T13:37:29","guid":{"rendered":"https:\/\/www.kemalarikan.com\/ayin-yayini"},"modified":"2023-11-29T12:47:45","modified_gmt":"2023-11-29T09:47:45","slug":"publication-of-the-month","status":"publish","type":"page","link":"https:\/\/www.kemalarikan.com\/en\/publication-of-the-month","title":{"rendered":"Publication of the Month"},"content":{"rendered":"
\n

REM parameters in drug-free major depressive disorder: A systematic review and meta-analysis<\/h4>\n

Abstract:<\/strong> Previous studies revealed that rapid eye movement (REM) parameters, such as REM latency (RL) and REM density (RD) could be used as electrophysiological markers of depression. Yet these finding should be re-tested in a comorbid-free and drug-free sample.<\/p>\n

Objectives:<\/strong>The present systematic review and meta-analysis was conducted to investigate whether drug-free and comorbid-free patients with unipolar depression differentiate from controls with respect to the RL and RD.<\/p>\n

Methods:<\/strong> The PubMed and Web of Science databases were screened from inception to 23 January 2023 for case-control studies comparing RL and RD of patients with unipolar depression and controls. The primary outcome was the standard mean difference. The data were fitted with a random-effects model. Metaregressions were conducted to investigate patient characteristics and effect size. Publication bias assessment was checked by Egger\u2019s Regression and funnel plot asymmetry.<\/p>\n

Results:<\/strong>Among 43 articles accepted as eligible, 46 RL and 22 RD measurements were included in the meta-analysis. The results indicated shortened RL and increased RD in the patient group than controls. Neither Egger\u2019s regression nor funnel plot asymmetry were significant for publication bias.<\/p>\n

Conclusions:<\/strong> In conclusion, our results tested within drug-free and comorbid-free samples are in line with the literature.<\/p>\n

*** Mehmet K. Ar\u0131kan, Omer Uysal, Saakir G\u0131ca, Ozden Orhan, Reyhan \u0130lhan, Muhammed T. Esmeray, Hasan Bakay, Bar\u0131\u015f Metin, Oliver Pogarell, \u015eenol Turan. REM parameters in drug-free major depressive disorder: A systematic review and meta-analysis. Sleep Medicine Reviews 73 (2024) 101876.<\/a>\n<\/p><\/blockquote>\n","protected":false},"excerpt":{"rendered":"

REM parameters in drug-free major depressive disorder: A systematic review and meta-analysis Abstract: Previous studies revealed that rapid eye movement (REM) parameters, such as REM latency (RL) and REM density (RD) could be used as electrophysiological markers of depression. Yet these finding should be re-tested in a comorbid-free and drug-free sample. Objectives:The present systematic review […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-2266","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nPublication of the Month - Psychiatrist Prof. Dr. Kemal Ar\u0131kan<\/title>\n<meta name=\"description\" content=\"REM parameters in drug-free major depressive disorder: A systematic review and meta-analysis Abstract: Previous studies revealed that rapid eye movement\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kemalarikan.com\/en\/publication-of-the-month\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Publication of the Month - Psychiatrist Prof. Dr. Kemal Ar\u0131kan\" \/>\n<meta property=\"og:description\" content=\"REM parameters in drug-free major depressive disorder: A systematic review and meta-analysis Abstract: Previous studies revealed that rapid eye movement\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.kemalarikan.com\/en\/publication-of-the-month\" \/>\n<meta property=\"og:site_name\" content=\"Psychiatrist Prof. Dr. Kemal Ar\u0131kan\" \/>\n<meta property=\"article:modified_time\" content=\"2023-11-29T09:47:45+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.kemalarikan.com\/wp-content\/uploads\/2022\/04\/prof-dr-kemal-arikan-psikiyatrist.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1280\" \/>\n\t<meta property=\"og:image:height\" content=\"720\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@mkemalarikan\" \/>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Publication of the Month - 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