{"id":2204,"date":"2020-05-17T01:30:37","date_gmt":"2020-05-16T22:30:37","guid":{"rendered":"https:\/\/www.kemalarikan.com\/rtms-ile-tedaviye-direncli-depresyonda-bilissel-bozulmanin-iyilesmesi.html"},"modified":"2020-09-17T17:17:22","modified_gmt":"2020-09-17T14:17:22","slug":"healing-of-cognitive-impairment-with-rtms-in-treatment-resistant-depression","status":"publish","type":"post","link":"https:\/\/www.kemalarikan.com\/en\/healing-of-cognitive-impairment-with-rtms-in-treatment-resistant-depression.html","title":{"rendered":"Healing of Cognitive Impairment with RTMS in Treatment-Resistant Depression"},"content":{"rendered":"

The disorder experienced by a number of individuals with depression<\/strong> is closely associated with the cognitive symptoms of the disorder. Cognitive impairment negatively affects various living spaces of the individual, including job, family life, social life and domestic responsibilities.<\/p>\n

Repetitive transcranial magnetic stimulation (rTMS)<\/strong> is a non-invasive brain stimulation method that is quite promising for healing cognitive symptoms in treatment-resistant depression (TRD) Various neuropsychological studies have shown that there are cognitive deficiencies in various cognitive regions in depression, executive function included. It is known that executive function deficiencies associated with frontal lobe dysfunction are apparent in depressive patients.<\/p>\n

Recently, it has been shown that TRD is associated with increased inflammatory process. The inflammatory process has been reported to take part in the pathophysiology of depression. Cytokines can affect cognition in various mechanisms. Recent reports have shown that an increased inflammatory process weakens the functional brain connection that is closely associated with the cognitive dysfunction.<\/p>\n

A study analyzed whether the changes in cognitive functions<\/strong> were associated with the changes in inflammatory cytokines<\/strong> prior to and following the rTMS<\/strong> treatment. In the study, a high-frequency rTMS procedure was implemented on patients with TRD.<\/p>\n

Depressive symptoms<\/strong>, serum concentration<\/strong> (interleukin (IL) – 1\u03b2, IL-6 and tumor necrosis factor-\u03b1) and cognitive function of inflammatory cytokines<\/strong> were measured before and after the rTMS treatment.\u00a0The rTMS treatment substantially healed the depressive symptom scores and some cognitive dysfunction sub-scales.<\/strong><\/p>\n

This study showed that any partial changes in cognitive function are significantly correlated with the changes in IL-1\u03b2. The partial healing of the cognitive disorder through rTMS in this study can be attributed to the reduction of the peripheral IL-1 P levels.<\/p>\n

(For more detailed information, please read our article titled \u201c<\/em>Everything About Depression<\/em><\/a>\u201d).<\/em><\/p>\n

KAYNAK:<\/strong>
\n– https:\/\/www.kemalarikan.com\/en\/everything-about-depression.html<\/a>
\n– Tateishi, H., Mizoguchi, Y., Kawaguchi, A., Imamura, Y., Matsushima, J., Kunitake, H., \u2026 Monji, A. (2020). Changes in interleukin-1 beta induced by rTMS are significantly correlated with partial improvement of cognitive dysfunction in treatment-resistant depression: a pilot study. Psychiatry Research, 289, 112995. doi:10.1016\/j.psychres.2020.112995<\/p>\n","protected":false},"excerpt":{"rendered":"

The disorder experienced by a number of individuals with depression is closely associated with the cognitive symptoms of the disorder. Cognitive impairment negatively affects various living spaces of the individual, including job, family life, social life and domestic responsibilities.<\/p>\n","protected":false},"author":2,"featured_media":2006,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[501],"tags":[],"class_list":["post-2204","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-articles"],"acf":[],"yoast_head":"\nHealing of Cognitive Impairment with RTMS in Treatment-Resistant Depression<\/title>\n<meta name=\"description\" content=\"The disorder experienced by a number of individuals with depression is closely associated with the cognitive symptoms of the disorder. Cognitive impairment negatively affects various living spaces of the individual, including job, family life, social life and domestic responsibilities.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kemalarikan.com\/en\/healing-of-cognitive-impairment-with-rtms-in-treatment-resistant-depression.html\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Healing of Cognitive Impairment with RTMS in Treatment-Resistant Depression\" \/>\n<meta property=\"og:description\" content=\"The disorder experienced by a number of individuals with depression is closely associated with the cognitive symptoms of the disorder. Cognitive impairment negatively affects various living spaces of the individual, including job, family life, social life and domestic responsibilities.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.kemalarikan.com\/en\/healing-of-cognitive-impairment-with-rtms-in-treatment-resistant-depression.html\" \/>\n<meta property=\"og:site_name\" content=\"Psychiatrist Prof. Dr. Kemal Ar\u0131kan\" \/>\n<meta property=\"article:published_time\" content=\"2020-05-16T22:30:37+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-09-17T14:17:22+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.kemalarikan.com\/wp-content\/uploads\/2020\/05\/rtms-ile-tedaviye-direncli-depresyonda-bilissel-bozulmanin-iyilesmesi.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1280\" \/>\n\t<meta property=\"og:image:height\" content=\"720\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Kemal Ar\u0131kan\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@mkemalarikan\" \/>\n<meta name=\"twitter:site\" content=\"@mkemalarikan\" \/>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Healing of Cognitive Impairment with RTMS in Treatment-Resistant Depression","description":"The disorder experienced by a number of individuals with depression is closely associated with the cognitive symptoms of the disorder. 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